How Working Out During Your Period Can Stress Out the Body and Elevate Cortisol Levels
THE SCIENCE OF WELLNESS
Written by Ghaliah Almezani, MSc Biochemistry
7/13/20253 min read
When it comes to working out during your menstrual cycle, opinions are mixed. Some say it helps ease cramps and elevate mood — others feel fatigued, bloated, and emotionally drained. But what’s happening on a biochemical level during menstruation? Could intense workouts during your period actually increase cortisol and put added stress on your body?
🔬 Menstrual Cycle & Hormone Fluctuations: The Basics
Your menstrual cycle is divided into four phases: menstrual, follicular, ovulatory, and luteal. The menstrual phase — aka your period — is marked by the lowest levels of estrogen and progesterone.
These hormonal drops affect not just mood and energy, but also how your body responds to physical stress. Low estrogen reduces muscle repair ability and can impair glucose metabolism, making workouts feel harder than usual (Bruinvels et al., Front. Physiol., 2020).
đź§Ş Exercise = Stress. And Stress = Cortisol.
Cortisol is your primary stress hormone, produced by the adrenal glands. It helps regulate metabolism, blood sugar, and inflammation. Exercise naturally raises cortisol — that’s not a bad thing in moderation.
However, when the body is already under hormonal stress (like during menstruation), additional physical stress from high-intensity exercise can amplify cortisol release.
📚 Study Insight: A PubMed study by Hill et al. (2018) showed that women in the early follicular phase (right after menstruation starts) exhibited higher cortisol reactivity to physical stress compared to other phases of the cycle. This suggests menstruation may be a time of increased vulnerability to stress overload.
🩸 Why Exercise Feels Harder During Your Period
During menstruation, many women experience:
Fatigue due to lower iron levels (especially in heavy bleeding)
Water retention and bloating
Sleep disturbances
Mood shifts (PMS, anxiety)
These factors combined can weaken the body's stress response. Adding intense cardio or resistance training can trigger a disproportionate cortisol surge, which:
Slows down recovery
Increases muscle breakdown
Disrupts sleep further
Promotes fat storage (especially abdominal)
📚 PubMed Evidence: An article published in the European Journal of Applied Physiology (Kraemer et al., 2001) observed that women exercising during early menstrual phases showed greater catabolic stress, marked by elevated cortisol and impaired performance.
đź§ The Brain-Body Connection: HPA Axis Sensitivity
The hypothalamic-pituitary-adrenal (HPA) axis governs your stress response. During menstruation, the HPA axis becomes more sensitive to both emotional and physical stress.
📚 A study by Kudielka et al. (Psychoneuroendocrinology, 2009) found that women in the menstrual phase had exaggerated cortisol responses to both exercise and mental stress, due to hormonal downregulation.
This means even a moderate workout might feel intense — and your body might interpret it as a threat.
⚠️ When Elevated Cortisol Becomes a Problem
Chronically high cortisol can:
Disrupt your menstrual cycle (hypothalamic amenorrhea)
Increase abdominal fat
Decrease muscle mass
Suppress immunity
Lead to burnout and overtraining syndrome
In women, timing and intensity of workouts are essential to avoid over-stressing the body.
âś… What to Do Instead: Cycle-Syncing Your Fitness
You don’t have to skip exercise altogether during your period — just be gentler with your body.
Best workout options during menstruation:
Gentle yoga or pilates
Walking
Stretching or light mobility work
Rest days, especially on the first 2 days
📚 A 2020 study (Sports Med, McNulty et al.) concluded that training aligned with menstrual phases led to improved performance and reduced injury risk, suggesting the importance of syncing workouts with your cycle.
🌿 Final Thoughts
Your period is not a time of weakness — it’s a biologically sensitive window where your body needs support, not stress. Intense workouts may feel like self-discipline, but if they raise your cortisol and disrupt your cycle, it’s time to listen to your hormones.
Work with your cycle, not against it.
References (PubMed Studies):
Hill, E.E., Zack, E., Battaglini, C., et al. (2008). Exercise and circulating cortisol levels: the intensity threshold effect. J Endocrinol Invest, 31(7):587-91. PMID: 18787373
Bruinvels, G., Burden, R., Brown, N., et al. (2020). Sport, Exercise and the Menstrual Cycle: Where Is the Research? Front Physiol, 11:193. PMID: 32116926
Kraemer, W.J., et al. (2001). Hormonal responses to consecutive days of heavy-resistance exercise with or without nutritional supplementation. Eur J Appl Physiol, 85(1-2):34-41. PMID: 11560070
Kudielka, B.M., Hellhammer, D.H., et al. (2009). Sex differences in HPA axis responses to stress: a review. Psychoneuroendocrinology, 34(1):118–135. PMID: 19026487
McNulty, K.L., Elliott-Sale, K.J., Dolan, E., et al. (2020). The Effects of Menstrual Cycle Phase on Exercise Performance in Eumenorrheic Women: A Meta-Analytic Review. Sports Med, 50(10):1813–1827. PMID: 32710233
About me
Hi, I’m Ghaliah — a 28-year-old biochemist, mom of two, and the voice behind TheGlooDiaries. I hold a master’s degree in biochemistry and have published my research online, but my most meaningful transformation came after becoming a mother. I lost 23 kg postpartum — not through shortcuts, but by combining science, self-care, and resilience.
This space is a reflection of that journey. Here, I blend skincare, fitness, mental wellness, and biochemistry to help women feel empowered, informed, and in tune with their bodies. It’s not just about glowing — it’s about glowing with purpose.
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